Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 221 | 221 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 2 |
| 2 | AZT+DDI+NFV | 26 |
| 3 | 3TC+AZT+NFV+NVP | 29 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, L210W, T215Y | V106A | K122E, I135T, I142T, G196E, R211K |
| >221| codons 36-225 EICTEMEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIP HPAGLKKKKSATVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGTRYQYNVLPQGWKG SPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRTKIEELRQHLWKWGFY TPDKKHQKEP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G17D, D60E, I62V, L63P |
| >221| codons 1-99 PQITLWQRPLVTIKIGDQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYE QVPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |