Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| RES40 | RES40 | Brazil | 2002 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 96 |
| 2 | 3TC+D4T+NFV | 17 |
| 3 | 3TC+D4T+RTV | 17 |
| 4 | D4T+DDI+EFV | 65 |
| 5 | Unknown | 2 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N | K219Q | K101KE, K103N | K238T | I135V, E138A, S162C, E169D, K173T, Q174K, D185X, T200A, I202V, Q207E, F214L, V245Q | D186DN |
| >RES40| codons 1-252 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSVNNATPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRTKNPDIVI YQYMXNLYVGSDLEIGQHRAKVEELREHLLRWGLTTPDQKHQKEPPFLWMGYELHPDTWT VQPIQLPEKDSW |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12M, I15V, E35D, M36I, R57K, D60E, Q61D, L63T, G68E, H69R, I72T |
| >RES40| codons 1-99 PQITLWQRPLVMIKVGGQLKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYE DITIEICERKATGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |