Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 219 | 219 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 23 |
| 2 | AZT+ DDI | 24 |
| 3 | 3TC+ AZT | 44 |
| 4 | 3TC+ AZT+ D4T | 58 |
| 5 | 3TC+ AZT+ D4T+ NVP | 47 |
| 6 | 3TC+ AZT+ D4T+ NFV+ RTV | 124 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K70T, K219R | Y181C, G190A | T39A, E40F, K43E, K101Q, L109I, V118I, K122E, D123X, I135T, D177E, E194A, G196E, T200A, H208Y, R211K, D218E |
| >219| codons 36-225 EICAFLEEEGKISKIGPENPYNTPVFAIKKKNSTTWRKLVDFRELNKRTQDFWEVQLGIP HPAGLQKKKSVTVIDVGDAYFSIPLDEXFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKG SPAIFQSSMTKILEPFRKQNPEIVICQYMDDLYVASDLAIEQHRAKIEELRQYLWKWGFY TPERKHQKEP |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |