Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 214 | 214 | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 45 |
| 2 | 3TC+ AZT+ RTV | 60 |
| 3 | 3TC+ AZT+ NFV | 26 |
| 4 | 3TC+ D4T+ NVP | 121 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, M184V, T215F | Y181C, G190A | S68G, I135T, D177E, Q197K, T200A, F214L |
| >214| codons 36-225 EICTEMEKEGKISKIGPENPYNTPVFAIKKKDGTKWRKVVDFRELNKRTQDFWEVQLGIP HPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKG SPAIFQSSMTKILEPFRKQNPEIVICQYVDDLYVASDLEIGKHRAKIEELRQHLLRWGLF TPDKKHQKEP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12A, I13V, I64V, V77I |
| >214| codons 1-99 PQITLWQRPLVAVKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILVEICGHKAIGTVLIGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |