Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ACTG364_915 | 915 | U.S. | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 128 |
| 2 | AZT+DDC | 41 |
| 3 | AZT+3TC | 97 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, M184V | K219KE | V35L, K49R, T69TS, R83K, V90I, S162SN, T286A, V292I, I293V | Q161QE |
| >915| codons 1-296 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICTEMEKEGKISRIGPENPYNTPV FAIKKKDSSRWRKLVDFRELNKKTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFENSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDEKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEIVPLT |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12A, I15V, L19V, M36MI, K70KE |
| >915| codons 1-99 PQITLWQRPLVAIKVGGQVKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD QILIEICGHEAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Albrecht, MA | Nelfinavir, efavirenz, or both after the failure of nucleoside treatment of HIV infection.AIDS Clinical Trials Group 364 Study Team. | N Engl J Med, 2001 |