Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ACTG364_903 | 903 | U.S. | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 250 |
| 2 | AZT+DDC | 278 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| L74V, M184V | I31L, V35I, R83RG, K122E, I135T, S162Y, I178M, S251I | Q85QP, N136NS, I142IN, Y144YC |
| >903| codons 1-291 PISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALIEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKGTPDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTSNETPGNRCQYNVLPQGWKGSPAIFQYSMTKILEPFRKQNPDMVI YQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDIWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, L63P, V77I, V82I, I93L |
| >903| codons 1-99 PQITLWQRPLVSIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLIGPTPINIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Albrecht, MA | Nelfinavir, efavirenz, or both after the failure of nucleoside treatment of HIV infection.AIDS Clinical Trials Group 364 Study Team. | N Engl J Med, 2001 |