Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ACTG364_8 | 8 | U.S. | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 195 |
| 2 | AZT+DDI+3TC | 92 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, M184V, T215F | D67G, K219Q | K20R, V35IM, K43Q, K64N, K102Q, K104KN, I135L, S162H, T200A, Q207QH, D218E, L228LH, V245K, A272P, T286A |
| >8| codons 1-302 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICTEMEQEGKISKIGPENPYNTPV FAINKKGSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKNSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQHSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRAKIEELRHHLLRWGFFTPEQKHQKEPPFHWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVIPLTEEAE LE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12N, K14R, G16E, R41K, I62V, L63Q |
| >8| codons 1-99 PQITLWQRPLVNIRIEGQLKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD QVQIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Albrecht, MA | Nelfinavir, efavirenz, or both after the failure of nucleoside treatment of HIV infection.AIDS Clinical Trials Group 364 Study Team. | N Engl J Med, 2001 |