Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ACTG364_752 | 752 | U.S. | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 202 |
| 2 | AZT+DDC | 201 |
| 3 | AZT+DDC+3TC | 89 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215*Y | K219K*R | E28EG, E44ED, V60I, V118I, K122E, D123DG, I135IV, E169D, K173KN, V179VG, K201KN, I202V, Q207E, R211K, V245M | D177DV |
| >752| codons 1-247 PISPIETVPVKLKPGMDGPKVKQWPLTGEKIKALVEICTELEKDGKISKIGPENPYNTPI FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEGFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRNQNPVIGI YQYVDDLYVGSDLEIGQHRTNVEELREHLWKWGFYTPDRKHQKEPPFLWMGYELHPDKWT VQPIMLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15IV | R8R* |
| >752| codons 1-99 PQITLWQ*PLVTIKVGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Albrecht, MA | Nelfinavir, efavirenz, or both after the failure of nucleoside treatment of HIV infection.AIDS Clinical Trials Group 364 Study Team. | N Engl J Med, 2001 |