Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ACTG364_168 | 168 | U.S. | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDC | 166 |
| 2 | AZT+3TC | 90 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | E28K, K32E, E44D, K104N, K122E, I135V, S162C, T200A, E203D, H208FY, R211D, E224D, A272P, K277R, V292I | V118IL |
| >168| codons 1-295 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIEALVEICTELEKDGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKNSVTVLDVGDAYFSLPL DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRAKIDELRQYLWDWGFYTPDKKHQKDPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEIIPL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, E35D, N37ND, R41K, I62V, L63P, V77VI, I93L |
| >168| codons 7-99 QRPLVTIKVGGQLKEALLDTGADDTVLEDMDLPGKWKPKMIGGIGGFIKVRQYDQVPIEI CGHKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Albrecht, MA | Nelfinavir, efavirenz, or both after the failure of nucleoside treatment of HIV infection.AIDS Clinical Trials Group 364 Study Team. | N Engl J Med, 2001 |