Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| ACTG364_1212 | 1212 | U.S. | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 167 |
| 2 | AZT+DDI | 94 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, V75T | A62V, D67E, T215TI, K219Q | K20R, T27S, S68G, V118I, K122E, E203D, F214L, L228H, A272P, Q278QE, T286A | I37L |
| >1212| codons 1-297 PISPIETVPVKLKPGMDGPRVKQWPLSEEKIKALVELCTEMEKEGKISKIGPENPYNTPV FVIKKKEGTRWRKLTDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIDELRQHLLRWGLITPDQKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKELCKLLRGAKALTEVIPLTE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, E35D, M36ML, N37S, L63P |
| >1212| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDLSLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Albrecht, MA | Nelfinavir, efavirenz, or both after the failure of nucleoside treatment of HIV infection.AIDS Clinical Trials Group 364 Study Team. | N Engl J Med, 2001 |