Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA22062 | CA51032 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+IDV | 143 |
| 2 | 3TC+AZT+NFV | 242 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N, M46I, L90LM | L10F, N88D | T12I, I13V, I15V, R57K, I62V, L63P, V77I, I93L |
| >CA51032| codons 1-99 PQITLWQRPFVIVKVGGQLKEALLDTGADNTVLEEMNLPGRWKPKIIGGIGGFIKVKQYD QVPIEICGHKAIGTVLIGPTPVNIIGRDLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K219KN | K43E, E44EAD, T69TA, V118I, K122E, I135L, T200A, Q207E, H208Y, R211K, A272P, K277R, L283I, E297R |
| >CA51033| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEEDGKISKIGPENPYNTPV FAIKKKNSAKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIGQHRAKIEELREYLWKWGFYTPDNKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGTKALTEVIPLTREAE L |
References
| Author | Title | Citation |
| Mitsuya, Y | N88D facilitates the co-occurrence of D30N and L90M and the development of multidrug resistance in HIV type 1 protease following nelfinavir treatment failure. | ARHR, 2006 |