Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA8331 | CA50906 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+DDI+LPV | 43 |
| 2 | ABC+LPV+TDF | 26 |
| 3 | None | 48 |
| 4 | 3TC+ABC+ATV+RTV+TDF | 29 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82T, I84V | L10I, K14R, I15V, K20I, R41I, D60N, I62V, L63P, I64V, A71V, I85V |
| >CA50906| codons 1-99 PQITLWQRPIVTIRVGGQLIEALLDTGADDTVLEEMNLPGIWKPKIIGGIGGFVKVRQYN QVPVEICGHKVIGTVLVGPTPTNVVGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215Y | K219E | K64R, I135T, V179I, Q197K, T200A, Q207D, R211K, V245K, K277R, I293V |
| >CA50907| codons 1-301 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIRKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYVDDLYVGSDLEIGKHRAKIEELRDHLLKWGFYTPDEKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVVPLTEEAE L |
References
| Author | Title | Citation |
| Rhee, SY | Genotypic predictors of human immunodeficiency virus type 1 drug resistance. | PNAS, 2006 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |