Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1850 | CA50800 | U.S. | 2004 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+IDV | 80 |
| 2 | D4T+NVP+RTV | 65 |
| 3 | ABC+APV+D4T+RTV | 271 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, M46I, I54M, V82A, L90M | L33F, K43T | L10I, D60E, L63P, I64M, A71V, L89M, I93L |
| >CA50800| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTIFEEMNLPGRWTPKIIGGIGGFMKVRQYE QIPMEICGHKVIGTVLVGPTPANIIGRNMMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L210W, T215Y | K219E, N348I | K103N, Y181C | E6D, T7P, E44D, V60I, K66KR, A98S, K101Q, K122P, I135V, D177E, V179VAIT, R211K, L228R, A272P, K277R, I293V, E297A, I326V, G359S, K366R, I375V, T386I, T403MR, L469I, T470V, H483Y, K527N |
| >CA50801| codons 1-560 PISPIDPVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPI FAIKKRNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLQKNKSVTVLDVGDAYFSVPL DPDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEITI CQYMDDLYVGSDLEIGQHRTKIEELRQHLWKWGFYTPDEKHQKEPPFRWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTAEAE LELAENREILKEPVHGVYYDPSKDLVAEIQKQGQGQWTYQIYQEPFKILKTGKYARMRSA HTNDVRQLTEAVQKVATESIVIWGKIPKFKLPIQKETWEAWWREYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSIVDTTNQKTELQ AIYLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLINKEKVYLAWVPAHK GIGGNEQVDKLVSAGIRKVL |
References
| Author | Title | Citation |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |