<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
v620 v620 U.S. 1999 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 NRTI+ NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T69~, Y115F, Q151M, M184V A62V, V75T Y181C A98G, V108I K20R, K22R, I31R, S68G, K122E, F214L, K277Q, V292I, I293V  
>v620| codons 1-301
PISPIETVPVKLKPGMDGPRVRQWPLTEEKRKALVEICTEMEKEGKISKIGPENPYNTPV
FVIKKKDG~KWRKLTDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTILDVGDAFFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRKQNPDIVI
CQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVQQLCKLLRGTKALTEIVPLTEEAE
L

References
Author Title Citation
Winters, MA Genotypic, phenotypic, and modeling studies of a deletion in the beta3-beta4 region of the human immunodeficiency virus type 1 reverse transcriptase gene that is associated with resistance to nucleoside reverse transcriptase inhibitors. J Virol, 2000