Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| q489 | q489 | U.S. | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI+ NNRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, T69~ | K219R | Y181C | V35L, S48E, S68G, D123E, A158S, Q197E, R211K, F214L, H221HY |
| >q489| codons 1-272 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALLEICTEMEKEGKIEKIGPENPYNTPV FAIKRKDG~KWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRKQNPDIVI CQYMDDLYVGSDLEIGEHRTKIEELRQHLLKWGLTTPDRKYQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYA |
References
| Author | Title | Citation |
| Winters, MA | Genotypic, phenotypic, and modeling studies of a deletion in the beta3-beta4 region of the human immunodeficiency virus type 1 reverse transcriptase gene that is associated with resistance to nucleoside reverse transcriptase inhibitors. | J Virol, 2000 |