<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
v1966 v1966 U.S. 1999 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 NRTI+ NNRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67~, K70R, L74I, T215F T69G, K219Q L100I, K103N   E6D, K20R, T39N, K43E, K102R, D123E, K166R, D177E, V179I, G196K, T200I, Q207E, L228LR, V245K, A272P, K277R, I293V  
>v1966| codons 1-302
PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALVEICNELEEEGKISKIGPENPYNTPV
FAIKKK~SGRWRKIVDFRELNKRTQDFWEVQLGIPHPAGIKRNKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPEIII
YQYMDDLYVGSDLEIKQHRIKIEELREHLLRWGFFTPDQKHQKEPPFRWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEVVPLTEEAE
LE

References
Author Title Citation
Winters, MA Genotypic, phenotypic, and modeling studies of a deletion in the beta3-beta4 region of the human immunodeficiency virus type 1 reverse transcriptase gene that is associated with resistance to nucleoside reverse transcriptase inhibitors. J Virol, 2000