Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| con12 | con12 | Brazil | 1999 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 48 |
| 2 | 3TC+AZT | 37 |
| 3 | 3TC+AZT+RTV | 3 |
| 4 | 3TC+D4T+RTV | 78 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, V82L | F53L | L10I, T12S, G16A, E35D, M36I, N37D, I64V, H69K, K70E, V77I, C95S |
| >con12| codons 1-99 PQITLWQRPIVSIKIAGQLKEALLDTGADDTVLEDIDLPGRWKPKIIGGIGGLIKVRQYD QILVEICGKEAIGTVLIGPTPLNIIGRNLLTQIGSTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, L210W, T215Y | K219Q | K104S, T107P, I135T, I202V, E203D, H208Y, R211K, D218A | N136T |
| >con12| codons 36-225 EICTELEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIP HPAGLKKKSSVPVLDVGDAYFSVPLDKDFRKYTAFTIPSTTNETPGIRYQYNVLPQGWKG SPAIFQSSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRTKVDELRQYLWKWGFY TPAQKHQKEP |
References
| Author | Title | Citation |
| Machado, ES | Genotypic resistance and HIV-1 subtype in Brazilian children on dual and triple combination therapy. | J Clin Virol, 2004 |