Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| cs189 | cs189 | Brazil | 2001 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 7 |
| 2 | AZT+DDI | 57 |
| 3 | AZT+DDI+NFV | 48 |
| 4 | D4T+DDI+EFV | 3 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I15V, K20T, E35D, M36I, N37D, P39Q, R41K, R57K, D60E, Q61D, L89I |
| >cs189| codons 1-99 PQITLWQRPLVTIKVGGQLTEALLDTGADDTVLEDIDLQGKWKPKMIGGIGGFIKVKQYE DILIEICGHKAIGTVLVGPTPVNIIGRNIMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | E53D, K104R, V118I, D123E, I135T, E169D, K173A, Q174K, E204D, Q207E, R211K, F214L |
| >cs189| codons 36-225 EICTELEKEGKISKIGPDNPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIP HPAGLKKKRSVTVLDVGDAYFSIPLDKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKG SPAIFQSSMTKILDPFRAKNPDIVIYQYVDDLYVGSDLEIGQHRTKIEDLREHLLKWGLY TPDKKHQKEP |
References
| Author | Title | Citation |
| Machado, ES | Genotypic resistance and HIV-1 subtype in Brazilian children on dual and triple combination therapy. | J Clin Virol, 2004 |