<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
cs148 cs148 Brazil 2001 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT 132
2 AZT+ DDI 53
3 AZT+ 3TC 139
4 D4T+ 3TC+ NVP 56

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y K219Q Y181C, G190A A98G T39E, V60I, V106I, I135T, G196E, H208Y, R211K  
>cs148| codons 36-225
EICEELEKEGKISKIGPENPYNTPIFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIP
HPGGLKKKKSITVLDVGDAYFSVPLDKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKG
SPAIFQSSMTKILEPFRKQNPDIVICQYVDDLYVASDLEIEQHRTKIEELRQYLWKWGFY
TPDQKHQKEP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12I, L33V, R41K, R57K, Q61E, L63P, I64V  
>cs148| codons 1-99
PQITLWQRPLVIIKIGGQLKEALLDTGADDTVVEEMNLPGKWKPKMIGGIGGFIKVKQYD
EIPVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Machado, ES Genotypic resistance and HIV-1 subtype in Brazilian children on dual and triple combination therapy. J Clin Virol, 2004