Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| cs146 | cs146 | Brazil | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 84 |
| 2 | AZT+ DDI | 54 |
| 3 | AZT+ 3TC+ RTV | 156 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, L90M | Q58E | L10I, K20R, M36I, R41K, I62V, L63P, H69R, A71V |
| >cs146| codons 1-99 PQITLWQRPIVTIKIGGQLREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFVKVREYD QVPIEICGRKVIGTVLVGPTPANIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, V75M, M184V, T215F | V60I, V90I, I94L, I135T, S162Y |
| >cs146| codons 36-225 EICTELEKEGKISKIGPENPYNTPIFAIKKKNSTRWRKLMDFRELNKRTQDFWEIQLGLP HPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKG SPAIFQYSMTKILEPFRKQNPDIVIYQYVDDLYVGSDLEIGQHRTKIEELRQHLLRWGFF TPDKKHQKEP |
References
| Author | Title | Citation |
| Machado, ES | Genotypic resistance and HIV-1 subtype in Brazilian children on dual and triple combination therapy. | J Clin Virol, 2004 |