Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| cs143 | cs143 | Brazil | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 103 |
| 2 | AZT+ DDI | 32 |
| 3 | AZT+ 3TC | 113 |
| 4 | D4T+ 3TC+ NFV | 89 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | L10I, G16E, L19V, K20I, R41K, R57K, A71T, T74S, V77I, Q92K |
| >cs143| codons 1-99 PQITLWQRPIVTIKIEGQVIEALLDTGADDTVLEEMNLPGKWKPKIIGGIGGFIKVKQYD QILIEICGHKTIGSVLIGPTPVNIIGRNLMTKIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215Y | K43Q, V118I, K122E, I135T, S162C, D177N |
| >cs143| codons 36-225 EICTELEQEGKISKIGPENPYNTPVFAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIP HPAGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKG SPAIFQCSMTKILEPFRKQNPNIVIYQYVDDLYVGSDLEIGQHRTKIEELRQHLWRWGFY TPDKKHQKEP |
References
| Author | Title | Citation |
| Machado, ES | Genotypic resistance and HIV-1 subtype in Brazilian children on dual and triple combination therapy. | J Clin Virol, 2004 |