<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
cs142 cs142 Brazil 2001 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ DDI 54
2 AZT+ 3TC+ NFV 93

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N, M46L   I64V, A71V  
>cs142| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADNTVLEEMNLPGRWKPKLIGGIGGFIKVRQYD
QILVEICGHKVIGTVLVGPTPVNIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210W, T215Y V75A     K102Q, K122R, D123E, I142V, K173E, D177E, I178L, Q207K, R211Q  
>cs142| codons 36-225
EICTELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLADFRELNKRTQDFWEVQLGIP
HPAGLKQKKSVTVLDVGDAYFSVPLDREFRKYTAFTIPSINNETPGVRYQYNVLPQGWKG
SPAIFQSSMTKILEPFREQNPELVIYQYVDDLYVGSDLEIGQHRTKIEELRKHLWQWGFY
TPDKKHQKEP

References
Author Title Citation
Machado, ES Genotypic resistance and HIV-1 subtype in Brazilian children on dual and triple combination therapy. J Clin Virol, 2004