Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| cs141 | cs141 | Brazil | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 22 |
| 2 | AZT+DDI | 36 |
| 3 | 3TC+AZT | 31 |
| 4 | 3TC+D4T+RTV | 96 |
| 5 | 3TC+D4T+NFV+NVP | 64 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184I, L210W, T215Y | K219R | K103N, Y181C | E44D, V118I, K122E, E203K, H208Y, R211K, W212M, K223Q |
| >cs141| codons 36-225 EICTELEKDGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIP HPAGLKKNKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKG SPAIFQSSMTKILEPFRKQNPDIVICQYIDDLYVGSDLEIGQHRTKIKELRQYLWKMGFY TPDRKHQQEP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | F53L | L10I, I13V, K20R, E35D, M36I, N37S, R41K, I62V, L63P, I64V, H69Y, A71V |
| >cs141| codons 1-99 PQITLWQRPIVTVKIGGQLREALLDTGADDTVLEDISLPGKWKPKMIGGIGGLIKVRQYD QVPVEICGYKVIGTVLVGPTPVNVIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Machado, ES | Genotypic resistance and HIV-1 subtype in Brazilian children on dual and triple combination therapy. | J Clin Virol, 2004 |