<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
con28 con28 Brazil 1999 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ DDI 141

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12I, K14R, I15V, Q18E, E35D, M36I, R41K, R57K, Q61N, L63T, L89M  
>con28| codons 1-99
PQITLWQRPLVIIRVGGELKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
NITIEICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70R       T69A, K122G, T200A, F214L  
>con28| codons 36-225
EICTEMEKEGKISKIGPENPYNTPVFAIKKKDSARWRKLVDFRELNKRTQDFWEVQLGIP
HPAGLKKKKSVTVLDVGDAYFSVPLDGDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKG
SPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRAKIEELRQHLLRWGLT
TPDKKHQKEP

References
Author Title Citation
Machado, ES Genotypic resistance and HIV-1 subtype in Brazilian children on dual and triple combination therapy. J Clin Virol, 2004