<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
cs122 cs122 Brazil 2001 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ DDI 114

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12R, L19I, E35D, M36I, R41K, R57K, Q61N, L63S, E65D, L89M, C95S  
>cs122| codons 1-99
PQITLWQRPLVRIKIGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
NISIDICGHKAIGTVLVGPTPVNIIGRNMLTQIGSTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, T215Y K219Q     T39K, K43E, K122E, D123E, S162C, T200A, D218E  
>cs122| codons 36-225
EICKEMEEEGKISKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIP
HPAGLKKKKSVTVLDVGDAYFSVPLDEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKG
SPAIFQCSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRAKIEELRQHLLRWGFY
TPEQKHQKEP

References
Author Title Citation
Machado, ES Genotypic resistance and HIV-1 subtype in Brazilian children on dual and triple combination therapy. J Clin Virol, 2004