<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
cs121 cs121 Brazil 2001 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 AZT 209
2 AZT+ DDI 231

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, K70R, T215F       K49R, K122E, S162C, K173T, Q174K, D177E, I178L, Q207E, R211K  
>cs121| codons 36-225
EICTELEKEGKISRIGPENPYNTPVFAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIP
HPAGLKKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKG
SPAIFQCSMTKILEPFRTKNPELVIYQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFF
TPDKKHQKEP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L63P, C67Y, H69K, C95S  
>cs121| codons 1-99
PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYD
QIPIEIYGKKAIGTVLVGPTPVNIIGRNLLTQIGSTLNF

References
Author Title Citation
Machado, ES Genotypic resistance and HIV-1 subtype in Brazilian children on dual and triple combination therapy. J Clin Virol, 2004