<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
cs199 cs199 Brazil 2001 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 AZT+DDI 34
2 3TC+AZT 80
3 3TC+D4T+RTV 75

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, I54V, V82A L24I L10V, I15V, G16E, L19I, K20R, E35D, M36I, R57K, Q61D, L63V, E65D  
>cs199| codons 1-99
PQITLWQRPVVTIKVEGQIREALIDTGADDTVLEDINLPGRWKPKLIGGIGGFVKVKQYD
DIVIDICGHKAIGTVLVGPTPANIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, V75M, M184V, L210W, T215Y     A98G K43Q, E44D, V118I, K122E, I135T, S162C, D177N, G196E, E203K, Q207E, H208Y, R211K, K223Q  
>cs199| codons 36-225
EICTELEQDGKISKIGPENPYNTPVFAIKKKNSDKWRKLMDFRELNKRTQDFWEVQLGIP
HPGGLKKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKG
SPAIFQCSMTKILEPFRKQNPNIVIYQYVDDLYVGSDLEIEQHRTKIKELREYLWKWGFY
TPDKKHQQEP

References
Author Title Citation
Machado, ES Genotypic resistance and HIV-1 subtype in Brazilian children on dual and triple combination therapy. J Clin Virol, 2004