Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CP1902 | CP1902 | Luxembourg | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+APV+D4T | 104 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A, I84V | L10I, K20R, E35D, M36V, N37D, D60E, Q61E, I62V, L63P, A71V, V77I, I93L |
| >CP1902| codons 4-99 TLWQRPIVTIKIGGQLREALLDTGADDTVLEDVDLPGRWKPKMIGGIGGFVKVRQYEEVP IEICGHKVIGTVLIGPTPANVIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y115F, Q151M | A62V, V75I, F77L, F116Y | Y181C | T69N, K122E, K173Q, Q174R, I202V, Q207E, R211K, V245T |
| >CP1902| codons 38-247 CTEMEKEGKISKIGPENPYNTPVFVIKKKDSNKWRKLIDLRELNKRTQDFWEVQLGIPHP AGLKKKKSVTVLDVGDAFYSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP AIFQSSMTKILEPFRQRNPDIVICQYMDDLYVGSDLEIGQHRTKVEELREHLLKWGFTTP DKKHQKEPPFLWMGYELHPDKWTVQPITLP |
References
| Author | Title | Citation |
| Clevenbergh, P | Long-term virological outcome in patients infected with multi-nucleoside analogue-resistant HIV-1. | Antivir Ther, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |