<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CP1902 CP1902 Luxembourg 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 NRTI NA
2 3TC+APV+D4T 104

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A, I84V   L10I, K20R, E35D, M36V, N37D, D60E, Q61E, I62V, L63P, A71V, V77I, I93L  
>CP1902| codons 4-99
TLWQRPIVTIKIGGQLREALLDTGADDTVLEDVDLPGRWKPKMIGGIGGFVKVRQYEEVP
IEICGHKVIGTVLIGPTPANVIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
Y115F, Q151M A62V, V75I, F77L, F116Y Y181C   T69N, K122E, K173Q, Q174R, I202V, Q207E, R211K, V245T  
>CP1902| codons 38-247
CTEMEKEGKISKIGPENPYNTPVFVIKKKDSNKWRKLIDLRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAFYSVPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSP
AIFQSSMTKILEPFRQRNPDIVICQYMDDLYVGSDLEIGQHRTKVEELREHLLKWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPITLP

References
Author Title Citation
Clevenbergh, P Long-term virological outcome in patients infected with multi-nucleoside analogue-resistant HIV-1. Antivir Ther, 2002
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005