<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CP0402 CP0402 France 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 NRTI NA
2 DDI+ D4T+ NFV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N, L90M   I13IV, N37D, L63P, A71I  
>CP0402| codons 4-99
TLWQRPLVTVKIGGQLKEALLDTGADNTVLEEMDLPGRWKPKMIGGIGGFIKVRQYDQIP
IEICGHKIIGTVLVGPTPVNIIGRNLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, Q151M F77FL, F116Y     K122E, I135M, S162A, Q197E, V245VE  
>CP0402| codons 38-247
CTEMEKEGKISKIGPENPYNTPVFAIKKKNSTKWRKLVDLRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYYSVPLDEDFRKYTAFTIPSMNNETPGIRYQYNVLPMGWKGSP
AIFQASMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGEHRTKIEELRQHLLRWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIELP

References
Author Title Citation
Clevenbergh, P Long-term virological outcome in patients infected with multi-nucleoside analogue-resistant HIV-1. Antivir Ther, 2002
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005