Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CP0303 | CP0303 | France | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NRTI|NVP | NA |
| 2 | 3TC+AZT+SQV | 52 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, T69T_SSG, L210W, T215Y | A62AV | Y181YC | A98G | E40EK, K43E, K101KR, V118VI, K122KE, I135X, S162C, D177E, V179VI, M184X, T200A, R211K, L228H, Q242QK |
| >CP0303| codons 38-247 CTKLEEEGKISKIGPENPYNTPVFVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP GGLRKKKSVTVLDVGDAYFSIPLDEDFRKYTAFTIPSXNNETPGIRYQYNVLPQGWKGSP AIFQCSMTKILEPFRKQNPEIIICQYXDDLYVGSDLEIGQHRAKIEELRQHLWKWGFYTP DKKHQKEPPFHWMGYELHPDKWTVKPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46ML, G48GV, V82VA, L90LM | L10LI, M36I, N37E |
| >CP0303| codons 4-99 TLWQRPIVTIKIGGQLKEALLDTGADDTVLEEIELPGRWKPKLIVGIGGFIKVRQYDQIL IEICGHKAIGTVLVGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Clevenbergh, P | Long-term virological outcome in patients infected with multi-nucleoside analogue-resistant HIV-1. | Antivir Ther, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |