<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CP0937 CP0937 France 2000 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ D4T+ NFV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, L90M   K20I, N37S, L63P, A71T, V77I  
>CP0937| codons 4-99
TLWQRPLVTIKIGGQLIEALLDTGADDTVLEEMSLPGRWKPKIIGGIGGFIKVRQYDQIP
IEICGHKTIGTVLIGPTPVNIIGRNLMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T69S_SG, K70R, T215F A62V, D67E     V118VI, K122E, D123S, D177DE, Q207E, R211K  
>CP0937| codons 38-247
CTEMEKEGKISKIGPENPYNTPVFVIKKKESSRWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVTVLDVGDAYFSIPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPEIVIYQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGFFTP
DKKHQKEPPFLWMGYELHPDKWTVQPIVLP

References
Author Title Citation
Clevenbergh, P Long-term virological outcome in patients infected with multi-nucleoside analogue-resistant HIV-1. Antivir Ther, 2002
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005