Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CP0720 | CP0720 | France | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NVP | NA |
| 2 | 3TC+ABC+AZT+NFV | 52 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, Q151M, M184V | F77FL, F116Y, K219Q | Y181C | A98G, V108VI | T39A, K43Q, D67X, T69N, K101X, D123E, S134SG, S162Y, D177E, V179I, T200X, E203ED, Q207QH, D218E | D113DN |
| >CP0720| codons 38-247 CAEMEQEGKISKIGPENPYNTPVFAIKKKXSNRWRKLVDLRELNKRTQDFWEVQLGIPHP GGLXKKKSVTILDVGNAYYSVPLDKEFRKYTAFTIPGINNETPGIRYQYNVLPMGWKGSP AIFQYSMTKILEPFRKQNPEIIICQYVDDLYVGSDLEIGQHRXKIDELRHHLLRWGFTTP EQKHQKEPPFLWMGYELHPDKWTVQPIVLP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A, L90M | W6L, L10LV, K20M, M36V, K55R, R57K, I62V, L63P, H69K, A71I, I93M, C95F |
| >CP0720| codons 4-99 TLLQRPVVTIKIGGQLMEALLDTGADDTVLEEVNLPGRWKPKIIGGIGGFVRVKQYDQVP IEICGKKIIGTVLVGPTPANIIGRNLMTQMGFTLNF |
References
| Author | Title | Citation |
| Clevenbergh, P | Long-term virological outcome in patients infected with multi-nucleoside analogue-resistant HIV-1. | Antivir Ther, 2002 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |