Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| Pat14 | 14csf_Post | Italy | 1998 | HIV1 | B | CSF | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ 3TC+ D4T+ SQV | NA |
| 2 | None | NA |
| 3 | D4T+ RTV+ SQV | 8 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I47IL | L10I, I13V, G16E, L33V, E35D, N37T, R57K, I62V, L63T, I64V | C67Q |
| >14csf_Post| codons 1-99 PQITLWQRPIVTVKIEGQLKEALLDTGADDTVVEDMTLPGRWKPKMLGGIGGFIKVKQYD QVTVEIQGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35M, R83K, D123E, R211K |
| >14csf_Post| codons 1-234 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKKTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYEL |
References
| Author | Title | Citation |
| Cinque, P | Effect of genotypic resistance on the virological response to highly active antiretroviral therapy in cerebrospinal fluid. | ARHR, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |