<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
Pat14 14pla_BL Italy 1997 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 AZT+ 3TC+ D4T+ SQV NA
2 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13IV, G16E, L33LV, E35D, N37T, R57K, I62V, L63T, I64V, N83Y C67Q
>14pla_BL| codons 1-99
PQITLWQRPIVTVKIEGQLKEALLDTGADDTVVEDMTLPGRWKPKMIGGIGGFIKVKQYD
QVTVEIQGHKAIGTVLVGPTPVYIIGRNLLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184MV       V35M, T69TA, D123E, R211K, F214L  
>14pla_BL| codons 1-228
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSAKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYVDDLYVGSDLEIGQHRTKIEELRQHLLKWGLTTPDKKHQKEPPFL

References
Author Title Citation
Cinque, P Effect of genotypic resistance on the virological response to highly active antiretroviral therapy in cerebrospinal fluid. ARHR, 2001
Rhee, SY HIV-1 protease and reverse transcriptase mutations: Correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance. J Infect Dis, 2005