Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TC-60 | TC-60 | Zimbabwe | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ DDI | 26 |
| 2 | IDV+ ABC+ EFV | 78 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R | K101E, V106M | V108VI | V35T, T39A, S48T, K122P, D123S, K166R, K173T, Q174K, D177E, I178L, Q207E, F214L, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V |
| >TC-60| codons 1-304 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAEMEKEGKITKIGPENPYNTPV FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSMTILDVGDAYFSVPL DPSFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRTKNPELVI YQYMDDLYVGSDLEIGQHRTKIEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54IV, V82A | I15V, E35D, M36I, R41K, L63P, H69K, A71AT, I93L |
| >TC-60| codons 1-99 PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGKKTIGTVLVGPTPANIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Johnston, E | High frequency of syncytium-inducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment. | J Virol, 2003 |