Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TC-59 | TC-59 | Zimbabwe | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 25 |
| 2 | 3TC+ APV+ AZT | 26 |
| 3 | APV+ EFV | 21 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | P14Q, K20R, V35T, E36A, T39E, K122E, D123S, I135M, S162C, K173V, Q174KR, D177E, Y188X, T200A, Q207K, R211K, V241I, V245Q, A272S |
| >TC-59| codons 1-280 PISPIETVPVKLKQGMDGPRVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRVKNPEIVI YQYMDDLXVGSDLEIGQHRAKIEELRKHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT IQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLC |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, L63P, H69K, V82VI, L89M, I93L |
| >TC-59| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Johnston, E | High frequency of syncytium-inducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment. | J Virol, 2003 |