Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TC-57 | TC-57 | Zimbabwe | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ 3TC+ NVP | 64 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, K122E, S163T, T165I, K173T, Q174QK, D177E, T200A, I202V, Q207E, R211K, K238R, V245Q |
| >TC-57| codons 1-263 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSTMIKILEPFRTKNPEIVI YQYMDDLYVGSDLEIGQHRAKVEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDRWT VQPIQLPEKDSWTVNDIQKLVGK |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, Q18X, L19I, M36I, R41K, D60E, H69K, L89M, I93L |
| >TC-57| codons 10-99 LVSIKVGGXIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYEQILIEICGK KAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Johnston, E | High frequency of syncytium-inducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment. | J Virol, 2003 |