Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MDM_Pat19 | MDM19post | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+NFV | NA |
| 2 | APV+D4T+DLV | 52 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, I54M, L90M | T12S, K20I, E35D, M36I, I62V, L63P, A71AV, I72L |
| >MDM19post| codons 1-99 PQITLWQRPLVSIKIGGQLIEALLDTGADDTVLEDINLPGRWKPKLIGGIGGFMKVRQYD QVPIEICGHKVLGTVLVGPTPVNIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Murphy, MD | HIV protease mutations associated with amprenavir resistance during salvage therapy: importance of I54M. | J Clin Virol, 2004 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |