Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1847 | CA4954 | U.S. | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI | 78 |
| 2 | AZT+DDI | 156 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, K70R, L74V, T215F | K219Q | A33AG, V60I, K103R, V118I, K122E, I135T, K166T, E194EA, I202IT, H208HY, F214L, D218DE | I159L |
| >CA4954| codons 1-219 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKGLVEICTELEKEGKISKIGPENPYNTPI FAIKKKNSDRWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKRKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPALFQSSMTTILEPFRKQNPDIVI YQYMDDLYVGSDLAIGQHRTKTEELRQYLLRWGLFTPEQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M36I, I62V, L63P, I64V, H69Y |
| >CA4955| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD QVPVEICGYKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |
| Rhee, SY | Predictive Value of HIV-1 Genotypic Resistance Test Interpretation Algorithms. | J Infect Dis, 2009 |