Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK5013 | TK5013 | Denmark | 2002 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ SQV | 14 |
| 2 | 3TC+ AZT+ IDV | 11 |
| 3 | 3TC+ IDV+ D4T | 95 |
| 4 | 3TC+ D4T+ NFV | 135 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, D67N, T69D, K70KR, M184V, L210LW | K219KQ | K103KT | A98AG | V35I, E44ED, I47IL, S48X, V60I, D121H, K122E, I135IT, D177E, T200I, Q207E, R211K, T215X, V245K, D250DE, S251SI, I257IL, A272PS, K281KR, L282C, T286A, I293V |
| >TK5013| codons 1-319 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIEICTELEKDGKLXKIGPENPYNTPI FAIKKKNSDRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKTKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYVDDLYVGSDLEIGQHRIKIEELREHLWKWGFXTPDQKHQKEPPFLWMGYELHPDKWT VQPIKLPEKEIWTVNDLQKLVGKLNWASQIYPGIKVKQLCRCLRGAKALTEVVPLTEEAE LELAENREILKEPVHGVYY |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30DN, M46MI, I54IV, V82VA | L24LI | L10LI, I15IV, K20KR, E35D, M36I, N37DE, R41K, D60DE, Q61QH, I62V, L63LP, I64V, C67CY, H69HY |
| >TK5013| codons 1-99 PQITLWQRPIVTIKVGGQLREALIDTGADNTVLEDIDLPGKWKPKIIGGIGGFVKVRQYE HVPVEIYGYKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |