Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK5011 | TK5011 | Denmark | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ IDV | 34 |
| 2 | None | 144 |
| 3 | 3TC+ AZT | 59 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K20R, V35T, T39E, K122E, D123S, I135IT, F171Y, K173S, Q174K, D177E, V179I, T200TI, I202IV, Q207A, R211S, F214FL, P243H, V245E, E248D, A272P, T286A, I293V, P294A |
| >TK5011| codons 1-324 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPYRSKNPEIII YQYVDDLYVGSDLEIGQHRIKVEELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQHIELPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEVVALTEEAE LELAENREILKEPVHGVYYDPSKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13IV, K14KR, E35D, M36I, R41K, R57K, H69K, L89M |
| >TK5011| codons 1-99 PQITLWQRPVVTVRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |