Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK5010 | TK5010 | Denmark | 2003 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ RTV | 5 |
| 2 | 3TC+ AZT+ IDV | 22 |
| 3 | 3TC+ AZT+ NVP | 228 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, M184V | K219Q | K103N | K238T | V35T, E36A, T39E, E40D, K43R, T69N, A98S, K102R, K122E, D123S, I135T, A158S, K173AT, D177E, E194D, T200A, Q207N, F214L, L228R, V245Q, K249Q, A272P, T286TA, E291D, V292I, I293V | K30KI |
| >TK5010| codons 1-320 PISPIETVPVKLKPGMDGPKVKQWPLTEEIIKALTAICEDMEREGKISKIGPENPYNTPV FAIKKKDSNRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKRNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRAQNPEIVI YQYVDDLYVGSDLDIGQHRAKIEELRNHLLRWGLTTPDQKHQKEPPFRWMGYELHPDTWT VQPIQLPEQDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, I15V, L19I, M36I, N37D, R57K, L63S, H69K, L89M |
| >TK5010| codons 1-99 PQITLWQRPLVTVKVGGQIKEALLDTGADDTVLEEIDLPGRWKPKMIGGIGGFIKVKQYD QISIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |