Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| K5009 | TK5009 | Denmark | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ IDV+ RTV | 96 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V35T, E36A, T39E, S48T, D121H, K122E, I142T, T165L, K173T, Q174K, D177E, G196GR, T200A, Q207E, V245K, A272S, K277R, E291D, V292I, I293V, E297K, P313T, V317A, S322A |
| >TK5009| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSINNETPGTRYQYNVLPQGWKGSPAIFQSSMLKILEPFRTKNPEIVI YQYVDDLYVGSDLEIRQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGTKALTDIVPLTKEAE LELAENREILKETVHGAYYDPAKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L76V, V82A | L10LF | T12S, I15V, L19I, K20KR, M36I, R41K, I62V, L63P, H69K, L89M, I93L |
| >TK5009| codons 1-99 PQITLWQRPFVSIKVGGQIREALLDTGADDTVLEEINLPGKWKPKIIGGIGGFIKVRQYD QVPIEICGKKAIGTVVVGPTPANIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |