Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK5007 | TK5007 | Denmark | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ IDV | 97 |
| 2 | 3TC+ AZT+ IDV+ RTV | 164 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G73ST | L10I, T12S, I15V, L19I, E35D, M36I, N37S, R41K, K45R, I62V, L63P, H69K, I85V, I93L |
| >TK5007| codons 1-99 PQITLWQRPIVSIKVGGQIKEALLDTGADDTVLEDISLPGKWKPRMIGGIGGFIKVRQYD QVPIEICGKKAISTVLVGPTPVNIVGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | A98G | T7P, V35T, T39E, S48T, K64R, K122E, D123S, I135T, K173A, D177E, T200A, Q207N, R211K, V245Q, A272P, K275R, K277R, Q278N, R284RK, T286A, E291D, V292I, I293V, P294T, E297D, L301X |
| >TK5007| codons 1-309 PISPIEPVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIRKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRNHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVRNLCKLLKGAKALTDIVTLTDEAE FELAENREI |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |