Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK5003 | TK5003a | Denmark | 2003 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ NVP | 78 |
| 2 | ABC+ D4T+ LPV | 39 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14KR, E35D, M36I, R41K, I64V, K70R |
| >TK5003a| codons 1-99 PQITLWQRPLVTVRIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILVEICGHRAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103KN | V35T, K49R, V60I, D121Y, K122E, D123DE, E169D, D177E, I178IL, Q207G, R211K, V245K, D250E, A272P, K275R, K277R, Q278H, L282C, L283LI, T286A, I293V |
| >TK5003a| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL YEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRKQNPELVI YQYMDDLYVGSDLEIGQHRTKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIRVRHLCKCIRGAKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQ |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |