Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK4017 | TK4017 | Denmark | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ IDV+ RTV | 7 |
| 2 | None | 1 |
| 3 | 3TC+ ABC+ AZT | 91 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19T, M36I, R41K, L63P, H69K, I93L |
| >TK4017| codons 1-99 PQITLWQRPLVSIKVGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W | T215N | E138K | V35T, T39G, K43R, A98S, K122E, D123S, A158S, S162A, K173A, D177E, T200A, Q207E, R211K, V245Q, A272P, T286A, E291D, V292I |
| >TK4017| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICGELEREGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNKTPGIRYQYNVLPQGWKGSPSIFQASMTKILEPFRAQNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLWKWGFNTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIIPLTEEAE LELAENREILKEPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |