Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK4006 | TK4006 | Denmark | 2001 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ NFV | 83 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | E6D, V35T, S48T, V60I, K122E, D123NS, I135T, K173I, Q174K, D177E, I178L, V179I, Q207A, R211S, P243A, V245E, D250E, E291D, V292I, I293V, P294T, E312D, Q334P, G335D |
| >TK4006| codons 1-341 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKITKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPELII YQYVDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQAIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDIVTLTEEAE LELAENREILKDPVHGVYYDPSKDLIAEIQKQGPDQWTYQI |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N88S | L10F | I13V, I15V, K20I, E35N, M36I, R41K, K45R, H69K, L89I | R57Q |
| >TK4006| codons 1-99 PQITLWQRPFVTVKVGGQLIEALLDTGADDTVLENINLPGKWKPRMIGGIGGFIKVQQYD QILIEICGKKAIGTVLVGPTPVNIIGRSILTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |