Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK4003 | TK4003a | Denmark | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ NFV | 215 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215F | V35T, K122E, D123S, I135V, I142V, K173S, Q174K, D177E, V179I, T200A, Q207A, R211S, F214L, V245Q, D250E, S251X, A272AP, K275KQ, T286A, E291D, V292I, I293V, E312D | T216TR |
| >TK4003a| codons 1-320 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII YQYVDDLYVGSDLEIGQHRAKIEELRAHLLSWGLFRPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKEXWTVNDIQKLVGKLNWASQIYPGIQVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKDPVHGVYYD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V | L33I, N83D | L10V, I13V, K14R, G16E, A22V, E35D, M36I, R41K, K45R, L63T, H69R, K70R, L89I |
| >TK4003a| codons 1-99 PQITLWQRPVVTVRIEGQLKEVLLDTGADDTVIEDINLPGKWKPRMIGGIGGFVKVRQYD QITIEICGRRAIGTVLVGPTPVDIIGRNILTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |