Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK4002 | TK4002 | Denmark | 1999 | HIV1 | CRF01_AE | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ IDV | 8 |
| 2 | 3TC+ D4T+ RTV | 137 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, R41K, H69K, L89M |
| >TK4002| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | E6D, V35T, T39K, K43E, K122E, D123S, S162SC, T165TI, K173I, Q174K, D177E, T200TA, Q207A, R211S, K238R, V245E, T286A, A288T, E291D, V292I, I293V, E312T, V317A, I329V |
| >TK4002| codons 1-334 PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMIKILEPFRIKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDRWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKTLTDIVPLTEEAE LELAENREILKTPVHGAYYDPSKDLIAEVQKQGQ |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |