Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TK4001 | TK4001 | Denmark | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT+ NFV | 2 |
| 2 | 3TC+ AZT+ NVP | 64 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19T, M36I, R41K, Q61E, L63P, H69K, V82I, L89M, I93L |
| >TK4001| codons 1-99 PQITLWQRPLVSIKVGGQTKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD EIPIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K101E, G190A | V35T, T39E, S48T, K104R, K122E, D123N, I135IT, K173A, D177E, Q197K, T200A, Q207E, V245Q, A272P, K277R, E291D, V292I, I293V, K311KR, V314X, V317VA |
| >TK4001| codons 34-324 LTEICEEMEKEGKITKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLG IPHPAGLEKKRSVTVLDVGDAYFSVPLDENFRKYTAFTIPSTNNETPGIRYQYNVLPQGW KGSPAIFQSSMTKILEPFRAQNPEIVIYQYVDDLYVASDLEIGKHRAKIEELREHLLRWG FTTPDKKHQKEPPFLWMGYELHPDKWTVQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPG IKVRQLCKLLRGTKALTDIVPLTEEAELELAENREILREPXHGAYYDPSKD |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |